Aryl iodides
Apexbio Technology LLC Nintedanib (BIBF 1120) 656247-17-5 10mM (in 1mL DMSO)
Nintedanib (BIBF 1120 CAS 656247-17-5) is an orally bioavailable small-molecule tri-kinase inhibitor that targets vascular endothelial growth factor receptors (VEGFR1-3) fibroblast growth factor receptors (FGFR1-3) and platelet-derived growth factor receptors (PDGFR / ) By inhibiting these receptor pathways at nanomolar concentrations (IC50 20 100 nmol/L) Nintedanib disrupts angiogenesis signaling and demonstrates antiangiogenic activity It is extensively investigated in preclinical and clinical research for idiopathic pulmonary fibrosis (IPF) as well as oncology including non-small-cell lung carcinoma ovarian cancer colorectal cancer and hepatocellular carcinoma
Medchemexpress LLC Iodo-PEG7-alcohol | 98.0% | C14H29IO7 | 250 MG
Iodo-PEG7-alcohol is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This chemical is intended for research use only and is not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Appearance: liquid, colorless to light yellow
- Storage: -20°C, protect from light
- In solvent storage: -80°C for 6 months; -20°C for 1 month, protect from light